Review of Clinical and Technological Consideration for MRI-Guided Robotic Prostate Brachytherapy

Low Dose Rate Brachytherapy (LDR-BT) is a technique for treating localized prostate cancer by implanting radioactive seeds. In conventional practice, the delivery of seeds performed using transrectal ultrasonography (TRUS) imaging implant guidance and checked computed-tomography post-implant dosimetry. case TRUS, accuracy can be compromised due to sub-optimal imaging. Magnetic Resonance Imaging (MRI), however, known provide better soft-tissue contrast, therefore, increasing ability detect small lesions; that reason, integration intraoperative MRI in BT workflows has been investigated over last two decades. The fusion preoperative MR-images during TRUS-brachytherapy possible. However, image registration process introduces source uncertainty. Manual, real-time intra-operative LDR-BT challenging under confined space procedural workflows. This motivates development MRI-compatible robots BT, with potential advantages improved placement final this paper, state-of-art technological components compatible robots, especially LDR-BT, presented. systematic review helps us position an ongoing Cooperative project, developing MRI-guided robot adaptive LDR-BT. design approach includes integrating separate modules: imaging, dose planning, needles, robot.